IS COLLAGEN SAFE? – finally, the lid is lifted on hydrolysed collagen

Posted on May 03 2020

IS COLLAGEN SAFE? – finally, the lid is lifted on hydrolysed collagen

There are now literally hundreds of hydrolysed collagen products on the world market today with new brands popping up seemingly every week. So how do you know which one to choose? How do you even know if they are safe to consume or how much you should take?

Well let’s cut the promotional ‘spin’ and get straight to the facts.

Worldwide, authorities have continually attested to the safety of gelatin and hydrolysed collagen. Based on international research results, the World Health Organization (WHO), the European Commission for Health and Consumer Protection, and the European Food Safety Authority  have all confirmed that hydrolysed collagen is totally safe for human consumption. In the United States the Food and Drug Administration (FDA) has classified gelatin, from which collagen peptides are prepared, as a safe substance. 

Collagen has GRAS status (Generally Recognised As Safe ) with no recommended daily intake limit as it is a natural food ingredient in commonly consumed foods.

 The safety of hydrolysed collagen


The United States FDA reports that:

'No significant adverse findings other than rare hypersensitivity have been found in the examination of data from feeding and biochemical experiments. Thus, there is no evidence to demonstrate a hazard to the public at the level gelatin is consumed as a food or a food ingredient. Based on these considerations, the Select Committee concludes that: There is no evidence in the available information on gelatin that demonstrates or suggests reasonable grounds to suspect a hazard to the public when it is used at levels that are now current or that might reasonably be expected in the future'.

Apart from gelatin, peptones are also listed as GRAS. Peptones are a variable mixture of polypeptides, oligopeptides, and amino acids that are produced by partial hydrolysis of gelatin. According to the definition (peptide mix, produced by hydrolysis, source eg gelatin) this brand of collagen powder is a peptone.



Hydrolysed collagen’s GRAS status is backed by solid evidence including numerous independent scientific studies. 

This Japanese study is the first to investigate the biological safety of fish collagen in accordance with ISO standards. All tests for cell toxicity, sensitization, chromosomal aberrations, intracutaneous reactions, acute systemic toxicity, pyrogenic reactions, and hemolysis were negative according to the criteria of the ISO and the Ministry of Health, Labour and Welfare of Japan.

Most hydrolysed collagen is around 90% protein and its best not to take protein supplements if you have existing kidney disease . A high protein diet (appx >1.2g of protein/kg body weight) is proven to be harmful for people with existing kidney dysfunction. So if you have a preexisting kidney illness, see your doctor before supplementing with any protein powders including collagen.

However the overwhelming evidence proves that eating a high protein diet or supplementing with collagen hydrolysate does not harm the kidneys in healthy people.

Rarely, minor side effects, such as nausea, flatulence or dyspepsia, may occur in some people the first time they ingest collagen peptides.

The safety of collagen peptide and gelatin is widely recognized and reported.

So, finally, the facts don't lie.

It is proven that hydrolysed collagen is not only totally safe to consume, but is a bioactive ingredient that has been specifically developed to deliver multiple health benefits and functional properties. 











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