40UP

40UP is specifically formulated for adults over 40 who want to build or maintain lean muscle, support strength and improve body composition. Whether your goal is to feel more confident in your physique, perform better in the gym or stay active for years to come, 40UP was designed around the changing nutritional needs of muscle after 40.

Yes. While resistance training provides the greatest stimulus for building muscle, 40UP is equally suitable for active adults who enjoy walking, golf, surfing, tennis, cycling, hiking or simply want to maintain strength and mobility as they age. If your goal is to build or maintain muscle, incorporating resistance exercise into your weekly routine will help you achieve the best results.

Absolutely. Women experience the same age-related changes in muscle as men, including anabolic resistance. 40UP supports women who want to maintain lean muscle, strength and healthy body composition through every stage of life after 40.

40UP can be enjoyed as a convenient high-protein meal or snack when it's difficult to meet your daily protein needs through food alone. A balanced diet built around whole foods should always remain the foundation of good nutrition.

Yes. 40UP was designed as a daily nutritional strategy for muscle after 40. Consistency is one of the most important factors in supporting long-term muscle health.

Most protein powders are designed to increase protein intake. 40UP was formulated around the changing nutritional needs of adults over 40.

Every meaningful dose has a purpose. Each serve provides 37.3 g of protein and 3.5 g of leucine, with the leucine content deliberately selected after reviewing human research into protein, leucine, anabolic resistance and muscle protein synthesis.

It’s a formulation built around the biology of muscle after 40, rather than simply increasing the amount of protein in a serving.

40UP already provides 10 g of Peptan® collagen peptides in every serve as part of its purpose-built formulation. If your primary goal is supporting muscle after 40, many customers find 40UP provides everything they need in one convenient daily shake. If you have additional skin, joint or specific health goals, other products within the CollagenX range may complement your routine.

40UP combines whey protein and hydrolysed collagen because they provide different amino-acid profiles and serve different roles in the body.

Whey is rich in essential amino acids, particularly leucine, which is important for stimulating muscle protein synthesis. Collagen provides a much higher concentration of glycine, an amino acid that is particularly important for connective tissue and also has roles in muscle-cell function and protein metabolism.

Together, they provide a broader amino-acid profile than whey protein alone.

Glycine is one of the most abundant amino acids in collagen, but it also has important roles beyond connective tissue. It is involved in protein synthesis, muscle-cell function, glutathione production and cellular antioxidant defence.

Research has also found that glycine can help restore the muscle's response to leucine under conditions of anabolic resistance. This is one reason 40UP provides additional glycine alongside whey, collagen and leucine.

Glycine is not a replacement for complete protein or essential amino acids, but it plays several important roles in muscle biology. Research has shown that glycine availability can influence muscle-cell proliferation, protein synthesis, glutathione production and cellular oxidative stress. Experimental research has also found that glycine can restore the muscle's anabolic response to leucine when inflammation causes anabolic resistance.

There is evidence that glycine and leucine can work together in muscle metabolism. Leucine acts as an important trigger for muscle protein synthesis, while glycine has roles in protein synthesis, cellular energy and antioxidant defence.

In an experimental model of inflammation-related anabolic resistance, glycine restored the muscle protein-synthesis response to leucine. Human research is still needed to determine how strongly this translates into greater muscle growth in healthy people.

40UP wasn't created by simply adding ingredients to a protein powder.

It was developed by asking a different question: what does muscle after 40 actually need?

The formula combines 35.7 g of protein with 3.5 g of leucine, 3 g of creatine and 10 g of Peptan® collagen peptides, alongside additional glycine, MCTs, prebiotic fibre, vitamin D₃, magnesium, zinc and niacinamide. Each meaningful ingredient was selected for a defined role within a formulation designed around the changing nutritional needs of muscle after 40. 

It's not about putting more ingredients into a tub. It's about putting the right ingredients in, at meaningful amounts, for a reason.

The evidence behind 40UP comes from the published research supporting the nutritional principles and individual ingredients that informed its development, including research into anabolic resistance, muscle protein synthesis, leucine, creatine and Peptan® collagen peptides.

We don't believe a study on one ingredient should automatically be presented as proof that an entire finished formula has been clinically tested. Instead, we show you the research that informed the formulation and explain why each meaningful ingredient and dose was selected.

You can explore the published research behind the formulation in the 40UP Evidence File.

Because ingredients added to a health-focused product should have a clear nutritional or functional purpose, and artificial sweeteners don't meet that standard for us.

CollagenX deliberately avoids artificial sweeteners because growing research has raised concerns about their potential effects on metabolic health, the gut microbiome and appetite regulation. While the evidence varies between individual sweeteners and continues to develop, we believe there is little reason to include them when they provide sweetness rather than nutritional value.

The same principle applies to colours, preservatives, gums and fillers. 40UP is already a more complex formulation than our pure collagen products because it has been purpose-built around the nutritional needs of muscle after 40. That complexity should come from ingredients with a defined role in the formulation, not from ingredients added simply to improve appearance, texture, shelf life or marketability.

That's why 40UP is made without artificial sweeteners, colours or preservatives, and without gums or fillers. It's a deliberate formulation choice: what goes into 40UP should earn its place.